性心理干预对乳腺增生患者报告结局(PRO)的影响

目的:探讨性心理干预对患者报告结局(PRO)及乳腺增生治疗作用的影响。方法:采用填写问卷的方法对2014年4月至2015年3月门诊接诊的2253名乳腺增生患者进行调查,其中性生活不满意1017人,按随机数字法分为两组,对照组508人:口服乳块消胶囊、岩鹿乳康片;观察组509人:在对照组基础上附加性心理测评,干预措施为性心理咨询和指导训练。每周复诊评估,至患者性生活满意。干预后分别在6个月、12个月进行随访调查。调查数据采用SPSS19.0软件进行统计分析,P<0.05表示差异有统计学意义。结果:45.14%(1017/2253)的乳腺增生患者存在性生活不满意。通过性心理咨询、针对性进行婚姻、家庭、子女教育以及性爱技巧等方面的指导训练可以有效提高性生活满意度(P<0.05)。观察组在性心理干预6个月、12个月时PRO与对照组比较有统计学差异,观察组优于对照组(P<0.05),12个月时两组疗效有统计学差异(P<0.05),观察组优于对照组。6个月时两组疗效比较无统计学差异(P>0.05)。结论:乳腺增生患者约45.14%存在性生活不满意,通过性心理咨询指导可以提高性满意度,改善PRO和疗效,可能让患者长期受益。

Effect of psychological intervention on the patient reported outcomes (PRO) of patients with breast hyperplasia

Objectives:To explore the effect of psychological intervention on patient reported outcomes (PRO) and the treatment of breast hyperplasia.Methods:Questionnaire survey was conducted among the 2253 patients with breast hyperplasia from April 2014 to March 2015,where the 1017 people with dissatisfied sex life were randomly divided into two groups,the control group (n =508) taking oral Rukuaixiao capsule and Yanlu Rukang tablet and the observing group (n =509) additionally receiving psychological interventions including sexual advice and guidance with weekly assessment until satisfaction.Follow-up survey was conducted 6 and 12 months after intervention.The data collected was analyzed using SPSS19.0 software,where P ＜ 0.05 indicated significant difference.Results:45.14％ (1017/2253) of patients with breast hyperplasia were dissatisfied with their sexual life.Psychological intervention including psychological counseling,targeted guidance on marriage,family,children 's education and sex skills could improve the satisfaction on sex life (P ＜0.05).Difference in the PRO at 6 and 12 months' follow up between the two groups was significant,better in the observation group (P ＜ 0.05) Differences at 12 months' follow up was of statistical significance (P ＜ 0.05) but difference at 6 month was not (P ＞ 0.05).Conclusion:45.14％ of patients with breast hyperplasia are dissatisfied with their sexual life and psychological counseling and intervention can improve the sexual satisfaction and the efficacy of PRO,hereby bringing long-term benefit.