卵巢组织冷冻保存和移植的研究进展

卵巢组织冷冻移植作为育龄女性癌症患者保存生育力和恢复内分泌功能的治疗方案之一,发挥着越来越重要的作用,它甚至是青春期女性患者的唯一选择。但是,卵巢组织冷冻移植比较复杂,其过程包括卵巢组织的获取、卵巢组织的冷冻复苏、冻融后的活力检测、复苏后再移植等步骤,而每个步骤又有诸多影响因素,都会影响冷冻保存和移植的效果。本文对卵巢组织冷冻保存和移植的各主要环节进行了论述,并阐述了该技术现存的主要问题及该领域的新进展。

Research progress on ovarian tissue cryopreservation and transplantation

It is clear that ovarian tissue cryopreservation and transplantation are playing a more and more important role in providing fertility preservation and restoring ovarian endocrine function for female cancer patients at reproductive age,which is the only choice for adolescent girls.Ovarian tissue cryopreservation and transplantation process are very complex,including ovarian tissue harvesting,freezing-thawing of ovarian tissue,vitality testing post thawed,and each of them would impact the cryopreservation efficiency.This paper discussed main steps about the ovarian tissue cryopreservation and transplantation process,the main existing problems of this technology and the progress in this field.