| 纳洛酮的临床使用进展 |
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| 引用本文： | 卿帅,孙广运. 纳洛酮的临床使用进展[J]. 中国现代医生, 2012, 50(4): 36-38 |
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| 作者姓名： | 卿帅 孙广运 |
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| 作者单位： | 1. 泸州医学院研究生部,四川泸州 646000;四川省宜宾市第一人民医院麻醉科,四川宜宾 644000
2. 四川省宜宾市第一人民医院麻醉科,四川宜宾,644000 |
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| 摘 要： | 作为一种人工合成的非特异性阿片受体拈抗剂，纳洛酮能竞争性地阻断并取代阿片样物质与受体的结合，拮抗阿片肽产生所致的广泛病理生理效应。近年来，阿片肽在越来越多的疾病的病理过程被发现，因此纳洛酮的临床应用也越来越广泛。本文利用近年来纳洛酮临床应用的文献，综述纳洛酮临床应用最新进展。
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| 关 键 词： | 纳洛酮 阿片受体拮抗剂 临床应用 |
Development of naloxone in clinical application |
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| QING Shuai , SUN Guangyun. Development of naloxone in clinical application[J]. , 2012, 50(4): 36-38 |
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| Authors: | QING Shuai SUN Guangyun |
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| Affiliation: | 1.Graduate Department of Luzhou Medical College,Luzhou 646000,China;2.Department of Anesthesiology,the First People’s Hospital of Yibin City,Yibin 644000,China |
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| Abstract: | As a synthetic non-specific opioid receptor antagonist,nalxone can competitively block and replace the binding of opioids and receptor,therefore,it can antagonize wide range of pathophysiological effects caused by opioid peptides in various state.In recent years,opioid peptides are found in pathological process of more and more disease.Due to this,clinical use of naloxne is more widely.In this review,making use of literature in recent years,we sum up the latest clinical application of naloxone. |
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| Keywords: | Naloxone Opioid receptor antagonist Clinical application |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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