小剂量地塞米松预防根管治疗期间慢性尖周炎急性发作的临床研究

目的 探讨小剂量地塞米松对根管治疗期间慢性尖周炎急性发作的预防作用。方法 90倒下前磨牙慢性尖周炎患者以年龄性别分层，随机化配对分成A、B、C三组：A组每日口服地塞米松1．5mg，每日2次；B组每日口服地塞米松1．5mg，每日1次；C组为空白对照。分别于根管预备后6、24、48小时记录VAS评分。结果 A、B组与C组VAS评分经方差分析，差异具有高度统计学意义。A、B组VAS评分均值t检验差异无统计学意义。结论每日口服地塞米松1．5mg可有效预防根管治疗期间慢性尖周炎急性发作。

Clinical study on oral microdosage of dexamethasone to prevent IAE

Objective To evaluate the effect of the microdosage dexamethasone on prophylaxis of IAE. Methods After routine root canal preparation, 90 patients with chronic apicitis in lower premolar were allocated to 3 groups and stratified random according to age and sex: A) Dexamethasone 1. 5mg/12hrs for 2 days, B) Dexamethasone 1. 5mg/24h for 2 days, C) The control group. The VAS score of each patient was recorded at 6, 24, 48 hrs. Results The VAS scores of group A and B decreased and was significantly superior to group C, while there was no significant difference between group A and B. Conclusion Oral microdosage of dexamethasone to prevent IAE is an effective, practical, and safe method.