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Therapy for Pulmonary Arterial Hypertension in Adults: Update of the CHEST Guideline and Expert Panel Report
Authors:James R. Klinger  C. Gregory Elliott  Deborah J. Levine  Eduardo Bossone  Laura Duvall  Karen Fagan  Julie Frantsve-Hawley  Steven M. Kawut  John J. Ryan  Erika B. Rosenzweig  Nneka Sederstrom  Virginia D. Steen  David B. Badesch
Affiliation:1. Brown University, Providence, RI;2. Intermountain Healthcare and the University of Utah School of Medicine, Murray, UT;3. University of Texas Health Science Center at San Antonio, San Antonio, TX;4. A. Cardarelli Hospital, Naples, Italy;5. OhioHealth/The Ohio State University, Columbus, OH;6. University of South Alabama, Mobile, AL;7. CHEST, Glenview, IL;8. Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA;9. University of Utah, Salt Lake City, UT;10. Columbia University Medical Center, New York, NY;11. Children’s Hospitals and Clinics of Minnesota, Minneapolis, MN;12. Georgetown University Medical Center, Washington, DC;13. University of Colorado School of Medicine, Aurora, CO
Abstract:
Keywords:evidence-based medicine  guidelines  pulmonary arterial hypertension (PAH)  6MWD  6-min walk distance  AHRQ  Agency for Healthcare Research and Quality  CHEST  American College of Chest Physicians  COI  conflict of interest  ERA  endothelin receptor antagonist  FC  functional class  FDA  Food and Drug Administration  GRADE  Grading of Recommendations, Assessment, Development and Evaluation  HR  hazard ratio  IPAH  idiopathic pulmonary arterial hypertension  MID  minimally important difference  PAH  pulmonary arterial hypertension  PDE5I  phosphodiesterase type-5 inhibitor  PH  pulmonary hypertension  PICO  population, intervention, comparator, outcome  SSc-PAH  scleroderma-spectrum of disease and PAH  SSRI  selective serotonin reuptake inhibitor  WHO  World Health Organization
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