小型猪在肾脏疾病研究中的应用

随着对小型猪研究的不断深入,其作为人类疾病模型的优势日益明显,在生物医学研究中的应用也日趋增多。比较解剖学和生理学研究表明,小型猪的诸多生物学特性均与人类极为相似,尤其在肾脏的解剖和功能方面几乎是人类的复制品,使其在复制肾脏疾病模型,研究疾病发病机制和评估治疗策略等中具有无可替代的作用。本文将综述小型猪作为疾病动物模型在肾脏疾病研究中的应用。

The application of miniature pigs in kidney disease research

With the deepening of miniature pigs research, as the advantages of human disease model has become increasingly evident, the application in the biomedical research is also on the rise. Comparative anatomy and physiology studies have shown that many biological characteristics of miniature pigs are very similar to humans, especially in the anatomy and function of the kidneys is almost a replica of the human, make it in duplicate kidney disease model, research the pathogenesis of the disease and evaluate treatment strategies has an irreplaceable role. In this paper, we will review miniature pigs as the disease animal model application in kidney disease research.