| 纳米材料在止血方面的研究进展 |
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| 引用本文： | 王吉荣,贡海,卢光照,邓莉.纳米材料在止血方面的研究进展[J].药学实践杂志,2021,39(3):211-214. |
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| 作者姓名： | 王吉荣 贡海 卢光照 邓莉 |
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| 作者单位： | 海军军医大学药学院药剂学教研室，上海 200433;解放军第九六〇医院肿瘤科，山东 济南 250031 |
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| 摘 要： | 纳米材料因其独特的微观结构优势，已被广泛应用于材料制备、微电子与计算机技术、医学与健康、环境与能源等领域。与传统止血材料相比，纳米材料在一定程度上能提高传统止血药物的生物利用度和稳定性，增强药物的缓控与靶向释放，为现代化新型止血材料的发展奠定了良好的基础。对脂质体、纳米粒、自组装纳米肽、纳米纤维等多种纳米止血材料的前沿设计和应用进展进行了综述，最后简述纳米止血材料存在的问题和发展前景。
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| 关 键 词： | 纳米材料 止血 脂质体 纳米粒 自组装纳米肽 纳米纤维 |
| 收稿时间： | 2020/12/18 0:00:00 |
| 修稿时间： | 2021/4/21 0:00:00 |
Research progress in nanomaterials in hemostasis |
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| WANG Jirong,GONG Hai,LU Guangzhao,DENG Li.Research progress in nanomaterials in hemostasis[J].The Journal of Pharmaceutical Practice,2021,39(3):211-214. |
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| Authors: | WANG Jirong GONG Hai LU Guangzhao DENG Li |
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| Institution: | Department of Pharmaceutics, School of Pharmacy, Naval Medical University, Shanghai 200433, China;Department of Oncology, No.960 Hospital of PLA, Jinan 250031, China |
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| Abstract: | Nanomaterials, with the advantages of unique microstructure, have been widely used in the fields of material manufacturing, microelectronics and computer technology, medicine and health, environment and energy. Compared with traditional hemostatic materials, nanomaterials can improve the bioavailability and stability of traditional hemostatic drugs to a certain extent, enhance the controlled and targeted release of drugs, which lay a good foundation for the development of new-style modern hemostatic nanomaterials. This paper reviews the advanced design and application progress of various nanomaterials in hemostasis, such as liposomes, nanoparticles, self-assembled nano peptides, nanofibers, etc. Finally, the challenges and prospects of hemostatic nanomaterials are briefly described. |
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| Keywords: | nanomaterial hemostasis liposome nanoparticle self-assembled nano peptide nanofiber |
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