Determination of imipenem in human plasma, urine and tissue by high-performance liquid chromatography |
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Authors: | G Carlucci L Biordi C Vicentini M Bologna |
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Affiliation: | Dipartimento di Chimica, Università degli Studi dell'Aquila, Italy. |
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Abstract: | A simple and reliable HPLC method is described for the new beta-lactam antibiotic imipenem; suitable extraction procedures for the drug in human plasma, urine and prostatic tissue are described. The figures of merit for the assays are reported and examples given of their application. |
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