| N端脑钠肽、脑钠肽及ST2与心力衰竭患者严重程度相关性分析 |
| |
| 引用本文： | 温继梨,崔晓迎,陈凤英. N端脑钠肽、脑钠肽及ST2与心力衰竭患者严重程度相关性分析[J]. 中国医药导报, 2013, 0(2): 76-77,80 |
| |
| 作者姓名： | 温继梨 崔晓迎 陈凤英 |
| |
| 作者单位： | 内蒙古医科大学附属医院急救中心 |
| |
| 摘 要： | 目的明确N端脑钠肽（NT-pro-BNP）、脑钠肽（BNP）及ST2与心力衰竭患者严重程度相关性,探讨其对心力衰竭的诊断价值。方法选取我院2009年1月～2012年7月收集的心力衰竭患者354例,按纽约心脏协会（NYHA）心功能标准进行分级。所有入组病例均详细询问病史,入院后在常规检查的基础上完善NT-pro-BNP、BNP、ST2检查。结果与对照组比较,心力衰竭组NT-pro-BNP、BNP、ST2血浓度水平明显升高;心力衰竭组患者NT-pro-BNP、BNP、ST2血浓度水平在不同分级组间差异有统计学意义（P〈0.05、P〈0.01）;Spearman相关性分析显示,NT-pro-BNP、BNP、ST2血浓度水平随着心力衰竭程度的加重而加重;通过构建ROC曲线显示NT-pro-BNP、BNP、ST2曲线下面积分别为0.970、0.785及0.980。结论 NT-pro-BNP、BNP、ST2指标与心力衰竭患者严重程度呈相关性,可用于心力衰竭严重程度的评估,并可用于心力衰竭患者的诊断。其中NT-pro-BNP是诊断心力衰竭最敏感的标志物之一。
|
| 关 键 词： | 心力衰竭 ST2 脑钠肽 N端脑钠肽 |
Correlation analysis of N-terminal brain natriuretic peptide,brain natriuretic peptide and ST2 with heart failure severity |
| |
| WEN Jili,CUI Xiaoying,CHEN Fengying. Correlation analysis of N-terminal brain natriuretic peptide,brain natriuretic peptide and ST2 with heart failure severity[J]. China Medical Herald, 2013, 0(2): 76-77,80 |
| |
| Authors: | WEN Jili CUI Xiaoying CHEN Fengying |
| |
| Affiliation: | Emergency Center,the Affiliated Hospital of Inner Mongolia Medical University,Inner Mongolia Region,Hohhot 010010,China |
| |
| Abstract: | Objective To understand the correlation of N-terminal brain natriuretic peptide（NT-pro-BNP）,brain natriuretic peptide（BNP） and ST2 with severity of heart failure,and thus to investigate the diagnostic values of these indicators.Methods 354 cases of heart failure admitted to our hospital from January 2009 to July 2012 were classified according to the New York Heart Association（NYHA） heart function standard.All patients were asked in detail about medical history and completed NT-pro-BNP,BNP and ST2 check on the basis of routine examination after admission.Results Compared with control group,NT-pro-BNP,BNP and ST2 blood concentration levels were significantly increased in the heart failure group;There were significant differences in NT-pro-BNP,BNP and ST2 blood concentration levels between different classification groups（P 0.05,P 0.01）;Spearman correlation analysis showed that NT-pro-BNP,BNP and ST2 blood concentration levels increased with the severity of heart failure;ROC curve showed that the correlation coefficients for NT-pro-BNP,BNP and ST2 were 0.970,0.785 and 0.980 respectively.Conclusion NT-pro-BNP,BNP and ST2 indicators are positively related to the severity of heart failure,thus it can be used for the assessment of the severity of heart failure and also for the diagnosis of heart failure.Among the three indicators,NT-pro-BNP is the most sensitive markers in the diagnosis of heart failure. |
| |
| Keywords: | Heart failure ST2 Brain natriuretic peptide N-terminal brain natriuretic peptide |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
