妊娠糖尿病患者血清中硒、锌、铜、钙含量分析

目的:检测妊娠糖尿病(GDM)患者血清中微量元素硒、锌、铜、钙的含量,探讨其与GDM的关系。方法:采用原子分光光度计分别检测78例GDM孕妇和72例正常孕妇血清中硒、锌、铜和钙的含量。结果:GDM组孕妇血清中微量元素硒、锌及钙的含量明显低于正常对照组(P<0.000 1);而铜的含量,GDM组却显著高于正常对照组(P<0.000 1)。结论:微量元素硒、锌、铜、钙在GDM的发生和发展过程中具有重要的作用。GDM组孕妇体内存在微量元素的代谢紊乱,应加强孕妇的饮食指导,适时补充硒、锌、钙等。

Analysis on serum selenium,zinc,copper,and calcium contents in patients with gestational diabetes mellitus

Objective:To detect the contents of serum selenium,zinc,copper,and calcium in patients with gestational diabetes mellitus(GDM),and explore their relationships with GDM.Methods:The contents of serum selenium,zinc,copper,and calcium in 78 patients with GDM and 72 normal pregnant women were detected by atomic absorption spectrophotometer.Results:The serum contents of selenium,zinc,and calcium in GDM group were statistically significantly lower than those in normal control group(P<0.000 1);but the serum content of copper in GDM group was statistically significantly higher than that in normal control group(P<0.000 1).Conclusion:Selenium,zinc,copper,and calcium play important roles in occurrence and development of GDM.Metabolic disorder of trace elements exists in pregnant women with GDM,dietary guidance for pregnant women should be enhanced;selenium,zinc,and calcium should be complemented reasonably.