|
|||||
|
|
| 血小板内皮细胞黏附分子-1与肿瘤 | |
| 引用本文： | 刘芳,贾晓艳,王若雨. 血小板内皮细胞黏附分子-1与肿瘤[J]. 国际肿瘤学杂志, 2014, 41(1): 4-7 |
| 作者姓名： | 刘芳 贾晓艳 王若雨 |
| 作者单位： | 116001大连大学附属中山医院肿瘤内科（刘芳、王若雨）；大连大学附属新华医院病理科（贾晓艳） |
| 基金项目： | 国家自然科学基金（30970869） |
| 摘 要： | 血小板内皮细胞黏附分子-1（PECAM-1）是免疫球蛋白超家族中的一种黏附分子,高表达于内皮细胞.近年来研究发现,PECAM-1与肿瘤的发生、血管生成、细胞凋亡以及耐药均相关,可能对肿瘤的诊断与治疗产生重要影响. |
| 关 键 词： | 抗原,CD31 肿瘤 新生血管化,病理性 细胞凋亡 抗药性,肿瘤 |
Platelet endothelial cell adhesion molecule 1 and tumor |
|
| LIU Fang,JIA Xiao-Yan,WANG Ruo-Yu. Platelet endothelial cell adhesion molecule 1 and tumor[J]. Journal of International Oncology, 2014, 41(1): 4-7 | |
| Authors: | LIU Fang JIA Xiao-Yan WANG Ruo-Yu |
| Affiliation: | Department of Oncology, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, China |
| Abstract: | Platelet endothelial cell adhesion molecule 1 (PECAM 1) is a adhesion molecule of the immunoglobulin superfamily, which is highly expressed in endothelial cells. Recent studies show that PECAM 1 is related with tumorigenesis, angiogenesis, apoptosis and drug resistance, which may exert a significant influence on the diagnosis and treatment of tumor. |
| Keywords: | Antigens, CD31 Neoplasms Neovascularization, pathologic Apoptosis Drug resistance, neoplasm |
| 本文献已被 维普 等数据库收录！ | |
| 点击此处可从《国际肿瘤学杂志》浏览原始摘要信息 | |
| 点击此处可从《国际肿瘤学杂志》下载免费的PDF全文 | |