407例梅毒调查分析

目的:探讨近期本区域梅毒的流行病学及血清学特征。方法:回顾性分析2009年我科全年确诊的梅毒患者的性别、年龄、职业、文化程度、传播情况及血清学特点。结果:梅毒患者男女比例为1∶1.41,发病年龄主要集中在21~40岁,女性患者年龄明显小于男性,差异有显著统计学意义(P<0.05),绝大部分患者为已婚有性伴(332/407),文化程度主要以初中为主,高学历患者少,职业中无业、工人、农民占前3位,仅75人承认近3月内有非婚性伴,其中46人从未使用安全套,每次使用安全套患者仅有10人,3人近3月内使用过毒品。男性梅毒患者血清TRUST滴度以高滴度为主,女性患者低滴度相对较高,差异有显著统计学意义(P<0.05)。结论:本地区梅毒以女性、初中文化、无业、工人和农民居多,梅毒的防治也应将这些人群作为重点防治对象。

Epidemical investigation of syphilis in 407 cases

Objective：To explore the current epidemiological and serological characteristics of syphilis in Wuhu area.Methods： 407 cases of syphilis diagnosed in our department in 2009 were reviewed concerning the sexes,ages,occupation,educational background,mode of transmission and serological characteristics.Results： Totally,the male to female ratio was 1∶1.41,the age of infection ranged from 21 to 40 and the female patients were typically younger than the males,which was significantly different（P〈0.05）.A large portion of the infections had spouses（332/407）,and the educational levels were primarily within 9 years of schooling.The infection was less seen in highly educated subjects.The top 3 on the list of infections came with the jobless,workers and farmers.Only 75 patients admitted having had extra-marital sexual activity in the past three months,of which 46 had never used condom,10 adhered to condom use for each intercourse and 3 had drug use within the 3 months.Males were found with higher syphilis titers,whereas lower titers were commonly seen in female cases by TRUST（Toluidine Red Unheated Serum Test）,which suggested significant statistical difference（P〈0.05）.Conclusion： Syphilis was commonly prevalent in female population and those of lower educational level,jobless,workers and farmers in Wuhu area,suggesting that those subjects should be targeted in this disease control and prevention.