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| 微小RNAs在骨与软骨组织中的调节作用 | |
| 引用本文： | Zeng D,He C. 微小RNAs在骨与软骨组织中的调节作用[J]. 中国修复重建外科杂志, 2011, 25(6): 677-680 |
| 作者姓名： | Zeng D He C |
| 作者单位： | 长沙民政职业技术学院康复医学系;四川大学华西医院康复科; |
| 摘 要： | 目的对微小RNAs(microRNAs,miRNAs)在骨与软骨组织中的调控作用和作用机制作一综述。方法广泛查阅近年来有关miRNAs在骨与软骨组织的调控作用及作用机制的文献,进行总结与分析。结果 miRNAs是近年来骨关节疾病研究的热点,越来越多研究显示其在骨与软骨组织形成和代谢过程中,对于细胞分化、细胞基质分泌等方面发挥重要的调控作用,但确切机制尚不清楚。结论 通过对miRNAs在骨与软骨组织中的调控作用及作用机制的研究,可能为了解退行性骨关节疾病开辟新的领域。 |
| 关 键 词： | 微小RNAs 成骨细胞 破骨细胞 软骨 软骨细胞 |
Role of microRNAs on regulation of bone and cartilage tissue |
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| Zeng Dexin,He Chengqi. Role of microRNAs on regulation of bone and cartilage tissue[J]. Chinese journal of reparative and reconstructive surgery, 2011, 25(6): 677-680 | |
| Authors: | Zeng Dexin He Chengqi |
| Affiliation: | ZENG Dexin1,HE Chengqi2.1Department of Rehabilitation,Changsha Social Work College,Changsha Hunan,410004,P.R.China,2Department of Rehabilitation,West China Hospital,Sichuan University. |
| Abstract: | Objective To review the regulation and mechanism of the microRNAs(miRNAs) in the bone and cartilage tissue.Methods Recent literature concerning the regulation and mechanism of the miRNAs in the bone and cartilage tissue was extensively reviewed,summarized,and analyzed.Results Recently miRNAs is a hot topic in the bone and cartilage tissue.More and more materials show its important regulatory role in osteogenesis and cartilage growth and regeneration,but the definite mechanisms have not been clear yet.Conclu... |
| Keywords: | microRNAs Osteoblast Osteoclast Cartilage Chondrocyte |
| 本文献已被 CNKI PubMed 等数据库收录！ | |