急性缺血性卒中患者PagT及双侧颈内动脉狭窄程度的变化

目的:探讨血小板聚集率及颈内动脉狭窄与脑梗塞发病的关系。方法:测定120例急性脑梗塞患者及60例正常人的血小板聚集率(1.5min.MAR),B型多谱勒超声断层扫描检测颅外段颈内动脉狭窄程度。结果:脑梗塞组的血PagT1min与正常对照组比较有显著差异(P<0.05),PagT5min、MAR与对照组比较有非常显著差异(P<0.01),脑梗塞组B超检测颈内动脉中度以上狭窄占62.5%,正常对照组中度以上狭窄占35%,两组比较有非常显著差异(P<0.005)。结论:血小板聚集率升高及颅外段颈内动脉中度以上狭窄,与脑梗塞密切相关。

Variations of Platelet Aggregation Rate and Internal Carotid Artery Stenosis in Patients with Cerebral Infarction

Objective: To observe the relationship between platelet aggregation rate,internal carotid artery stenosis and occurrence of cerebral infarction.Method: The platelet aggregation test(PagT 1min,PagT 5min,MAR)and levels of the external cervical segment of internal carotid artery stenosis detected by B type ultrasonic tomographic scanning were performed in 120 cases of cerebral infarction patients and 60 normal controls. Result: There was significant difference between patients and controls in the PagT 1min(P<0.05).The differences of PagT 5min and MAR between the two groups were very significant(P<0.01).The occurrence rate of internal carotid stenosis above the mediate level is 62.5% while the rate is 35% in the controls. There was very significant difference between two groups (P<0.005).Conclusion: The increase of platelet aggregation rate and stenosis of the external cervical segment of the internal carotid artery above the mediate level are related to the occurrence of cerebral infarction.