| 高通量透析膜在血液透析中的应用 |
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| 引用本文： | 石磊. 高通量透析膜在血液透析中的应用[J]. 中国组织工程研究与临床康复, 2011, 15(25). DOI: 10.3969/j.issn.1673-8225.2011.25.035 |
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| 作者姓名： | 石磊 |
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| 作者单位： | 湖北民族学院附属医院肾内科,湖北省恩施市,445000 |
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| 摘 要： | 背景:高通量膜具有很高的通透性及溶质转运性能,透析中能有更多相对分子质量较大的溶质从血液转运到透析液中,故称之为高通量透析,属于一种高效血液净化治疗方法.目的:总结近年高通量透析膜在血液透析中的应用现状.方法:由作者应用计算机检索维普数据库,检索时限2000-02/2008-10.检索关键词:高通量透析膜;血液透析;临床应用.纳入标准:①高通量透析膜在血液透析中的应用.②实验结果叙述与材料有关的临床应用问题.排除标准:重复研究或较陈旧文献.根据纳入排除标准共保留相关文献12篇.结果与结论:与低通量血液透析相比可清除β2微球蛋白,降低透析患者血脂、血磷及甲状旁腺素水平,减轻炎症反应、氧化应激及血管内皮变化,不影响维持性血液透析患者血浆细胞因子及内毒素水平,对尿素氮、肌酐等小分子的清除也优于常规透析.因此,高通量透析可预防血液透析患者的远期并发症如肾性骨病,动脉硬化,并可改善食欲不振,高血压症状,提高透析的充分性.
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| 关 键 词： | 高通量透析膜 血液透析 临床应用 并发症 生物材料 |
High-flux dialysis membranes in hemodialysis |
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| Shi Lei. High-flux dialysis membranes in hemodialysis[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2011, 15(25). DOI: 10.3969/j.issn.1673-8225.2011.25.035 |
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| Authors: | Shi Lei |
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| Affiliation: | Shi Lei Department of Nephrology,Affiliated Hospital,Hubei Institute for Nationalities,Enshi 445000,Hubei Province,China |
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| Abstract: | BACKGROUND:High-flux membrane is characterized as high permeability and solute transport properties.During dialysis,many solutes with relative large molecular weight transport from the blood into the dialysis fluid,called as high-flux dialysis,which is an efficient blood purification treatment.OBJECTIVE:To summarize the application of high-flux membranes in hemodialysis.METHODS:A computer based search of VIP database was performed to retrieve articles published from 2000-02 to 2008-10 using keywords of high... |
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