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Rasmussen's Encephalitis with Concomitant Cortical Dysplasia: The Role of GluR3
Authors:Cheryl Ann Palmer&dagger  ,James D. Geyer,Janice M. Keating,Frank Gilliam,Ruben I. Kuzniecky&Dagger  ,Richard B. Morawetz&Dagger  ,E. Martina Bebin§  
Affiliation:Department of Neurology, The University of Alabama at Birmingham, Alabama, U.S.A.;Divisions of Neuropathology, The University of Alabama at Birmingham, Alabama, U.S.A.;Divisions of Neurosurgery, The University of Alabama at Birmingham, Alabama, U.S.A.;Department of Pediatrics, The Children's Hospital of Alabama, Birmingham, Alabama, U.S.A.
Abstract:
Summary: The role of the glutamate receptor GluR3 in Rasmussen's encephalitis is actively under investigation. Autoimmune processes with this receptor as the target are currently theorized. We provide an additional case of pathologically proved Rasmussen's encephalitis (with concomitant cortical dysplasia) in the presence of antibodies against the GluR3 receptor.
Keywords:Rasmussen's encephalitis    GluR3 receptor    Cortical dysplasia    Glutamate
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