门诊质子泵抑制剂应用分析及合理性评价

目的 分析门诊质子泵抑制剂的应用现状及合理用药情况,为临床用药提供参考.方法 采用回顾性调查方法,对该院2012年1～12月门诊患者质子泵抑制剂的应用分布、用药金额、用药频度、药物利用指数、日均费用、用药合理性等情况进行分析.结果 使用频度前3位的是兰索拉唑肠溶片、奥美拉唑肠溶片、雷贝拉唑肠溶片;用药金额前3位的是泮托拉唑注射剂、兰索拉唑肠溶片、雷贝拉唑肠溶片;药物利用指数大多接近1;处方合格率为96.05%,不合理的主要原因为无指征用药.结论 该院门诊应用质子泵抑制剂的合理性有待提高.

The application analysis and reasonable evaluation of proton pump inhibitor in outpatient

Objective To analysis the application and the reasonable evaluation of proton pump inhibitor （PPI） in outpatient in order to provide reference. Methods Retrospective analysis of the distribution of applications, the amount of medication, medication frequency, drug utilization index, the average daily cost of medication is reasonable of PPI from January to December 2012 in our hospital outpatient. Results Top 3 DDDs drugs were lansoprazole enteric-coated tablets, omeprazole enteric-coated tablets, rabeprazole sodium enteric-coated tablets. Top 3 total sum drugs were pantoprazole sodium for Injection, lansoprazole enteric-coated tablets,rabeprazole sodium enteric-coated tablets. The drug use indexes （DUI）of most drugs were less than 1. The rate of rational use was 96.05% ,the main reason of irrationality was not obvious PPI indications. Conclusion The rationality of PPI utilization remains to be improved.