| 拉米夫定联合胸腺五肽治疗慢性乙型肝炎临床观察 |
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| 引用本文： | 郭荣光,李新建,韩亚芳,李云峰,宋予娟. 拉米夫定联合胸腺五肽治疗慢性乙型肝炎临床观察[J]. 中国医药导报, 2007, 4(21): 7-8 |
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| 作者姓名： | 郭荣光 李新建 韩亚芳 李云峰 宋予娟 |
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| 作者单位： | 河南省新乡市传染病医院肝病科,河南新乡,453000 |
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| 摘 要： | 目的:观察拉米夫定联合胸腺五肽治疗慢性乙型肝炎的疗效。方法:选择慢性乙型肝炎42例,分为治疗组20例,对照组22例,两组均给予拉米夫定100mg/d,同时治疗组给予胸腺五肽1mg,随后两组继续给予拉米夫定100mg/d,总疗程52周。结果:两组ALT、TBil复常率无显著性差异(P>0.05),但HBVDNA及HBeAg阴转率有显著性差异(P<0.05),治疗组完全应答率显著高于对照组(P<0.05)。结论:拉米夫定联合胸腺五肽能显著提高抗HBV的疗效。
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| 关 键 词： | 拉米夫定 胸腺五肽 慢性乙型肝炎 |
Clinical observation of lamivudine combined with thymopentin in the treatment of patients with chronic hepatitis B |
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| GUO Rong-guang,LI Xin-jian,HAN Ya-fang,LI Yun-feng,SONG Yu-juan. Clinical observation of lamivudine combined with thymopentin in the treatment of patients with chronic hepatitis B[J]. China Medical Herald, 2007, 4(21): 7-8 |
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| Authors: | GUO Rong-guang LI Xin-jian HAN Ya-fang LI Yun-feng SONG Yu-juan |
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| Abstract: | Objective:To observe the effect of treatment with lamivudine combined with thymopentin on chronic hepatitis B.Methods:42 cases with chronic hepatitis B were divided into treatment group(20 cases) and control group(22 cases).Both groups treated with lamivudine(100 mg/d),meanwhile,thymopentin was used in treatment group for 26 weeks,then both groups treated with lamivudine(100 mg/d).Both groups treated for 52 weeks in all.Results:The normalization rate of ALT and TBil had no significantly difference between two groups(P>0.05),but negative rate of HBVDNA and HBeAg had significantly difference between two groups(P<0.05),the completed response rate in treatment group were higher than that of control group(P<0.05).Conclusion:Lamivudine combined with thymopentin can improve the curative effect for chronic hepatitis B. |
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| Keywords: | Lamivudine Thymopentin Hepatitis B |
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