Anti-apoptotic effect of claudin-1 in tamoxifen-treated human breast cancer MCF-7 cells |
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| Authors: | Harue Akasaka Fuyuki Sato Satoko Morohashi Yunyan Wu Yang Liu Jun Kondo Hiroki Odagiri Kenichi Hakamada Hiroshi Kijima |
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| Affiliation: | 1.Department of Pathology and Bioscience,Hirosaki University Graduate School of Medicine,Hirosaki,Japan;2.Department of Pathology, College of Basic Medical Sciences,China Medical University,Shenyang,China;3.Department of Surgery,Hirosaki University Graduate School of Medicine,Hirosaki,Japan |
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| Abstract: | ![]()
Background Claudin-1 is a membrane protein of tight junctions, and is associated with the development of various cancers. However, the significance of claudin-1 expression in cancer cells is not well understood. Here, we showed for the first time the anti-apoptotic effect of claudin-1 in human breast cancer MCF-7 cells. |
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