| hCG/ATP-induced Leydig cell calcium channel reaction at different extracellular calcium ion concentration |
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| 引用本文： | Ting WU,Wei ZHANG,Yuan-Geng SUI,Jian-Ning ZHANG,Li-Rong WANG Department of Urology,First Affiliated Hospital,NanjingMedical University,Nanjing 210029,ChinaJiangsu Key Laboratory on Reproductive MedicineNanjing,China. hCG/ATP-induced Leydig cell calcium channel reaction at different extracellular calcium ion concentration[J]. Asian journal of andrology, 2003, 0(2) |
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| 作者姓名： | Ting WU Wei ZHANG Yuan-Geng SUI Jian-Ning ZHANG Li-Rong WANG Department of Urology First Affiliated Hospital NanjingMedical University Nanjing 210029 ChinaJiangsu Key Laboratory on Reproductive MedicineNanjing China |
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| 作者单位： | Ting WU，Wei ZHANG，Yuan-Geng SUI，Jian-Ning ZHANG，Li-Rong WANG Department of Urology，First Affiliated Hospital，NanjingMedical University，Nanjing 210029，ChinaJiangsu Key Laboratory on Reproductive MedicineNanjing，China |
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| 摘 要： | Objective: To study the calcium channel reaction of human Leydig cells induced by hCG/ATP at different extracellular calcium ion concentrations. Methods: The Leydig cell calcium ion concentration was examined with laser confocal microscope, when the cells were stimulated with hCG/ATP at different extracellular calcium contrations. Results: With calcium-containing extracellular fluid, the Leydig cells were sensitive to hCG stimulation and when the extracellular fluid was calcium-free, the Leydig cells did not respond to the stimulation. However, the Leydig cells did respond to ATP stimulation no matter the extracellular fluid contained calcium or not. Conclusion: In human Leydig cells, there are calcium channels sensitive to hCG and ATP. The extracellular calcium ion concentration plays an important role in the regulation of Leydig cell metabolism by hCG/ATP.
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hCG/ATP-induced Leydig cell calcium channel reaction at different extracellular calcium ion concentration</b></span></td>
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<td align="left" height="25" valign="top" colspan=2"><author>Ting WU,Wei ZHANG,Yuan-Geng SUI,Jian-Ning ZHANG,Li-Rong WANG. <title>hCG/ATP-induced Leydig cell calcium channel reaction at different extracellular calcium ion concentration[J]. Asian journal of andrology, 2003, 0(2)</td>
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<td align="left" height="25" valign="top" nowrap><b>Authors:</b></td><td width="92%" valign="top" align="left" ><a target='_blank' href='search.aspx?subject=medicine_health&major=wkx&orderby=referenced&field=author_name&q=%3cauthor%3eTing+WU&prev_q=%3cauthor%3eTing+WU'><author>Ting WU</a> <a target='_blank' href='search.aspx?subject=medicine_health&major=wkx&orderby=referenced&field=author_name&q=Wei+ZHANG&prev_q=Wei+ZHANG'>Wei ZHANG</a> <a target='_blank' href='search.aspx?subject=medicine_health&major=wkx&orderby=referenced&field=author_name&q=Yuan-Geng+SUI&prev_q=Yuan-Geng+SUI'>Yuan-Geng SUI</a> <a target='_blank' href='search.aspx?subject=medicine_health&major=wkx&orderby=referenced&field=author_name&q=Jian-Ning+ZHANG&prev_q=Jian-Ning+ZHANG'>Jian-Ning ZHANG</a> <a target='_blank' href='search.aspx?subject=medicine_health&major=wkx&orderby=referenced&field=author_name&q=Li-Rong+WANG&prev_q=Li-Rong+WANG'>Li-Rong WANG</a></td>
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<td align="left" height="25" valign="top" nowrap><b>Affiliation:</b></td><td width="92%" valign="top" align="left" ><author>Ting WU,Wei ZHANG,Yuan-Geng SUI,Jian-Ning ZHANG,Li-Rong WANG Department of Urology,First Affiliated Hospital,NanjingMedical University,Nanjing 210029,ChinaJiangsu Key Laboratory on Reproductive MedicineNanjing,China</td>
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<td align="left" height="25" valign="top" nowrap><b>Abstract:</b></td><td width="92%" align="left" valign="top"><abstract>Objective: To study the calcium channel reaction of human Leydig cells induced by hCG/ATP at different extracellular calcium ion concentrations. Methods: The Leydig cell calcium ion concentration was examined with laser confocal microscope, when the cells were stimulated with hCG/ATP at different extracellular calcium contrations. Results: With calcium-containing extracellular fluid, the Leydig cells were sensitive to hCG stimulation and when the extracellular fluid was calcium-free, the Leydig cells did not respond to the stimulation. However, the Leydig cells did respond to ATP stimulation no matter the extracellular fluid contained calcium or not. Conclusion: In human Leydig cells, there are calcium channels sensitive to hCG and ATP. The extracellular calcium ion concentration plays an important role in the regulation of Leydig cell metabolism by hCG/ATP.</td>
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<td align="left" valign="top" height="25" nowrap><b>Keywords:</b></td><td width="92%" valign="top" align="left" ><a target='_blank' href='search.aspx?subject=medicine_health&major=wkx&orderby=referenced&field=key_word&q=calcium+concentration&prev_q=calcium+concentration'>calcium concentration</a> <a target='_blank' href='search.aspx?subject=medicine_health&major=wkx&orderby=referenced&field=key_word&q=hCG&prev_q=hCG'>hCG</a> <a target='_blank' href='search.aspx?subject=medicine_health&major=wkx&orderby=referenced&field=key_word&q=ATP&prev_q=ATP'>ATP</a> <a target='_blank' href='search.aspx?subject=medicine_health&major=wkx&orderby=referenced&field=key_word&q=Leydig+cells&prev_q=Leydig+cells'>Leydig cells</a> <a target='_blank' href='search.aspx?subject=medicine_health&major=wkx&orderby=referenced&field=key_word&q=calcium+channel&prev_q=calcium+channel'>calcium channel</a></td>
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<td align="left" colspan="2" height="30"><b>本文献已被 <a href="http://www.cnki.com.cn/Article/CJFDTotal-YZNK200302020.htm" target="_blank">CNKI</a> 等数据库收录！</b></td>
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