抗真菌对慢性阻塞性肺病合并真菌感染治疗临床效果分析

目的探讨抗真菌对慢性阻塞性肺病合并真菌感染的临床治疗效果。方法选择笔者所在医院慢性阻塞性肺病合并真菌感染患者82例，将以上患者随机分为两组，观察组和对照组。两组患者等常规治疗。在以上治疗基础上对照组患者未用抗真菌治疗，观察组应用抗真菌药物治疗。两组患者在治疗期间观察其临床症状的改善情况，定期进行痰真菌培养。记录两组患者住院时间和死亡病例。结果观察组总有效率与对照组总有效率比较，差异有统计学意义（P〈0．05）。观察组住院时间和病死率分别与对照组比较，差异有统计学意义（P〈0．05）。结论慢性阻塞件肺病抗生素治疗期间应用抗真菌药能够显著改善患者临床症状，缩短住院时间和降低病死率，临床效果显著。

Clinical efficacy of antifungal treatment on chronic obstructive pulmonary disease complicated with fungal infection

Objective To explore the clinical efficacy of antifungal treatment on chronic obstructive pulmonary disease complicated withfungal infection. Methods 82 cases with chronic obstructive pulmonary disease complicated withfungal infection were selected, and they were divided into two groups, observation group and control group. The routine treatment was used to two groups, on the base of the routine treatment, antifungal treatment was given to observation group, antifungal treatment was not done to control group, the improvement of clinical symptoms was observed ; fungal culture was done regularly, the hospitalization time and mortality rate were recorded in two groups. Results The total effective rate in observation group compared with that in control group, there was statistical difference（ P 〈 0.05 ） ;The hospitalization time and mortality rate in observation group compared with that in chronic obstructive pulmonary disease control group, there was statistical difference（ P 〈 0. 05 ）. Conclusion antifungal treatment can improe the clinical symptoms ,shorten the hospitalization time and decrease mortality rate while antibiotic treatment on. the clinical efficacy is significant.