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An Exception to Tumour Neoangiogenesis in a Malignant Breast‐Lesion
Authors:Pascal A. T. Baltzer MD  Matthias Benndorf  Mieczyslaw Gajda MD  Werner A. Kaiser MD
Affiliation:1. Institute for Diagnostic and Interventional Radiology, FSU Jena, Germany;2. These authors contribute equally to this work.;3. Institute of Pathology, FSU Jena, Germany
Abstract:Abstract: Magnetic resonance‐mammography is regarded as the most sensitive diagnostic modality in the detection of breast cancer. It uses the tumour neoangiogenesis to depict lesions after intravenous contrast agent injection. It is said, that for tumours exceeding a diameter of three millimetres contrast agent enhancement is mandatory. In our case report we describe a rare tumour growth condition. We observed a large invasive carcinoma (18 millimetres diameter) without contrast enhancement in breast MRI due to an almost missing tumour neoangiogenesis. The cancer had a low cellularity and a strong desmoplastic reaction.
Keywords:breast  MRI  sensitivity
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