In vitro activity of fosfomycin against extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae: comparison of susceptibility testing procedures |
| |
| Authors: | de Cueto M López L Hernández J R Morillo C Pascual A |
| |
| Affiliation: | Departamento de Microbiología Hospital Universitario Virgen Macarena, Avda. Dr. Fedriani núm 3, 41009, Sevilla, Spain. m@marinadecueto.e.telefonica.net |
| |
| Abstract: | The agar dilution, broth microdilution, and disk diffusion methods were compared to determine the in vitro susceptibility of 428 extended-spectrum-beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae to fosfomycin. Fosfomycin showed very high activity against all ESBL-producing strains. Excellent agreement between the three susceptibility methods was found for E. coli, whereas marked discrepancies were observed for K. pneumoniae. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
