Affiliation: | 1. Institute of Applied Health Research, University of Birmingham, Birmingham, UK;2. Institute of Applied Health Research, University of Birmingham, Birmingham, UK Christopher Sainsbury, Jingya Wang and Krishna Gokhale authors are contributed equally.;3. Cegedim Health Data, Cegedim Rx, London, UK;4. The Health Improvement Network (THIN), London, UK;5. Institute of Clinical Sciences, University of Birmingham, Birmingham, UK Department of Critical Care, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK;6. Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK;7. Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK;8. Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK;9. Institute of Applied Health Research, University of Birmingham, Birmingham, UK Joint Senior Authors.;10. Institute of Applied Health Research, University of Birmingham, Birmingham, UK Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK Midlands Health Data Research UK, Birmingham, UK Joint Senior Authors. |