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Role of maternal tryptophan metabolism in allergic diseases in the offspring |
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| Authors: | Hui Xing Lau Sarah El-Heis Qai Ven Yap Yiong Huak Chan Cheryl Pei Ting Tan Neerja Karnani Karen Mei Ling Tan Elizabeth Huiwen Tham Anne Eng Neo Goh Oon Hoe Teoh Kok Hian Tan Johan Gunnar Eriksson Yap Seng Chong Mary Foong-Fong Chong Hugo Van Bever Bee Wah Lee Lynette P. Shek Keith M. Godfrey Evelyn Xiu Ling Loo |
| Affiliation: | 1. Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore City, Singapore;2. Medical Research Council Lifecourse Epidemiology Unit, Southampton, UK;3. Biostatistics Unit, Yong Loo Lin School of Medicine, National University of Singapore, Singapore City, Singapore;4. Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore City, Singapore;5. Allergy Service, Department of Paediatrics, KK Women’s and Children’s Hospital (KKWCH), Singapore City, Singapore;6. Respiratory Service, Department of Paediatrics, KK Women’s and Children’s Hospital (KKWCH), Singapore City, Singapore;7. Department of Maternal Fetal Medicine, KK Women’s and Children’s Hospital (KKWCH), Singapore City, Singapore;8. Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore City, Singapore Department of Obstetrics & Gynaecology and Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore City, Singapore Folkhälsan Research Center, Helsinki, Finland Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland;9. Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore City, Singapore Department of Obstetrics & Gynaecology and Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore City, Singapore;10. Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore City, Singapore Saw Swee Hock School of Public Health, National University of Singapore, Singapore City, Singapore;11. Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore City, Singapore Khoo Teck Puat-National University Children’s Medical Institute, National University Hospital, National University Health System, Singapore City, Singapore;12. NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK |
| Abstract: | |
| Keywords: | eczema kynurenine pathway nicotinamide tryptophan metabolism vitamin B3 |