闪光视觉诱发电位无创颅内压监测结合头颅CT的临床研究

目的:探讨闪光视觉诱发电位无创颅内压监测与头颅CT之间的相关性.方法:用无创颅内压监测仪对50例颅脑外伤患者进行动态颅内压监测,其中重型颅脑损伤者20例,中型23例,轻型7例；每次检测后行头颅CT检查并计分,分析其CT变化特征,并与颅内压值对照.结果:伤后同一时点,患者的颅内压和头颅CT计分比较,重型＞中型＞轻型(P＜0.05).中、重型颅脑损伤患者保守治疗组和手术治疗组的颅内压与头颅CT计分之间,组内比较具有相关性,计算相关系数分别为r=0.92和r--0.96,差异有统计学意义(P＜0.05).结论:闪光视觉诱发电位无创颅内压监测与头颅CT变化呈正相关,两者结合可以指导治疗并判断预后.

Clinical Research on Noninvasive Monitoring of Intracranial Ppressure (ICP) with Flash Visual Evoked Potential (FVEP) and Brain CT

Objective：To explore the correlation between noninvasive monitoring of intracranial pressure with flash visual evoked potential （FVEP） and brain CT. Methods ：50 patients with traumatic brain injury were monitored with FVEP, in which 20 cases were severe grade,23 cases were moderate grade,7 cases were minor grade. Then all cases had been examined by brain CT and scored. The variation features of CT were analyzed and the supervising data of ICP were compared. Results： The results between intracranial pressure and the brain CT score were compared at the same time point after injury, severe grade 〉 moderate grade 〉 minor grade （ P 〈 0.05 ）. There was a linear correlation in the moderate grade and severe grade for conservative and operation treatment between the noninvasive monitoring of ICP with FVEP and brain CT score r = 0.92 , r = 0.96 （ P 〈 0.05 ）. Conclusions ： Positive correlation between the noninvasive monitoring of ICP with FVEP and brain CT can be used to guide the treatment and to judge prognosis of patients with closed head trauma.