| A Clinical Study of Reversing Left Ventricular Hypertrophy in Hypertensive Patients by Adalat |
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| 作者姓名： | 张馥敏 许迪 雍永宏 陈莉 陆凤翔 |
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| 作者单位： | Zhang Fumin Xu Di Yong Yonghong Chen Li Lu Fengxiang Department of Cardiology，The First Affiliated Hospital of Nanjing Medical University，Nanjing\ 210029，P.R.China |
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| 摘 要： | ＡＣｌｉｎｉｃａｌＳｔｕｄｙｏｆＲｅｖｅｒｓｉｎｇＬｅｆｔＶｅｎｔｒｉｃｕｌａｒＨｙｐｅｒｔｒｏｐｈｙｉｎＨｙｐｅｒｔｅｎｓｉｖｅＰａｔｉｅｎｔｓｂｙＡｄａｌａｔＺｈａｎｇＦｕｍｉｎ（张馥敏）ＸｕＤｉ（许迪）ＹｏｎｇＹｏｎｇｈｏｎｇ（雍永宏）Ｃｈｅｎ...
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A Clinical Study of Reversing Left Ventricular Hypertrophy in Hypertensive Patients by Adalat |
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| Zhang Fumin,Xu Di,Yong Yonghong Chen Li,Lu Fengxiang.A Clinical Study of Reversing Left Ventricular Hypertrophy in Hypertensive Patients by Adalat[J].Journal of Nanjing Medical University,1997(1). |
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| Authors: | Zhang Fumin Xu Di Yong Yonghong Chen Li Lu Fengxiang |
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| Institution: | Zhang Fumin Xu Di Yong Yonghong Chen Li Lu Fengxiang Department of Cardiology,The First Affiliated Hospital of Nanjing Medical University,Nanjing\ 210029,P.R.China |
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| Abstract: | Fourteen outpatients (10 men, 4 women, mean age 52.6 yrs) suffered from essential hypertension complicated with left ventricular hypertrophy (LVH) detected by echocardiography were treated with Adalat 30 mg daily orally. After 3 months administration, casual high blood pressue was satisfactorily controlled. Both thickness of inter ventricular septum and left ventricular posterior wall were decreased (1.47 cm vs 1.34 cm P<0.01, 1.43 cm vs 1.32 cm P<0.01). Left ventricular mass (LVM) and left ventricular mass index (LVMI) calculated according to Devereux corrective formula were significantly reversed (279.4 g vs 247.4 g P<0.01, 162.7 g/m 2 vs 146.5 g/m 2 P<0.01). Meanwhile, cardiac performance was assessed, and the results demonstrated that Adalat could maintain left ventricular systolic function and improve left ventricular diastolic function which was resulted from regression of LVH. No side effects of Adalat were present in the study patients. |
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| Keywords: | hypertension left ventricular hypertrophy calcium channel blockers |
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