Effect of autologous sera on mitogenic stimulation of peripheral blood lymphocytes of mini-pigs chronically intoxicated with alcohol |
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Authors: | O. P. Ryabchikov N. A. Chuich S. P. Shmeleva G. V. Mardanova V. V. Osipov |
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Affiliation: | (1) Laboratory of Embryonal Histogenesis, Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow;(2) Laboratory of Biological Models, Russian Academy of Medical Sciences, Moscow |
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Abstract: | There are no statistically significant differences in the stimulation index for purified lymphocytes of control mini-pigs and mini-pigs with chronic alcohol intoxication. Autologous sera of control and experimental animals strongly suppress mitogen-induced blast transformation of lymphocytes without death of these cells. There are no statistically significant intergroup differences in the absolute number (per mm3) of T lymphocytes in peripheral blood. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, N o 7, pp. 89–91, July, 1994 Presented by N. K. Permyakov, Member of the Russian Academy of Medical Sciences |
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Keywords: | blast transformation lymphocyte autoserum alcoholism |
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