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血清促甲状腺素功能敏感度的测定及意义
引用本文:王德麟,陈琳,张志泉,王惠民. 血清促甲状腺素功能敏感度的测定及意义[J]. 南通医学院学报, 2008, 28(2): 100-102
作者姓名:王德麟  陈琳  张志泉  王惠民
作者单位:1. 南通大学附属南通第三医院检验科,南通,226006
2. 南通大学附属医院检验科
摘    要:
目的:对人血清促甲状腺素(TSH)功能敏感度的测定。方法:利用美国ABBOTT(雅培)公司的AXSYM和美国BECKMAN(贝克曼)公司的ACCESS全自动免疫系统,对14份不同浓度的血清标本连续测定10天,计算变异系数(CV)。通过统计学处理计算功能敏感度。结果:AXSYM系统与ACCESS系统功能敏感度分别为0.06 mIU/L和0.03 mIU/L。结论:功能敏感度由20%的批间变异系数得出,功能敏感度反映了临床的最低检出限度。

关 键 词:促甲状腺素  功能敏感度  变异系数
文章编号:1000-2057(2008)02-0100-03
修稿时间:2007-10-24

The determination and significance of functional sensitivity of human serum thyroid stimulating hormone
WANG Delin,CHEN Lin,ZHANG Zhiquan,et al. The determination and significance of functional sensitivity of human serum thyroid stimulating hormone[J]. ACTA Academiae Medicinae Nantong, 2008, 28(2): 100-102
Authors:WANG Delin  CHEN Lin  ZHANG Zhiquan  et al
Affiliation:WANG Delin1,CHEN Lin1,ZHANG Zhiquan2,et al
Abstract:
Objective: To measure the functional sensitivity of human serum TSH.Methods: Using entire automatic immune system AXSYM of American ABBOTT corporation and ACCESS of American BECKMAN corporation,measure the coefficient of variation of human serum specimen pools that covering the assay range in 14 different runs during 10 days.Compute the functional sensitivity by statistics processing.Results: The functional sensitivity of AXSYM system and ACCESS system respectively is 0.06 mIU/L and 0.03 mIU/L.Conclusion: The functional sensitivity is obtained by the 20% between-run coefficient and it reflects the lowest limit of clinical examination.
Keywords:Thyroid stimulating hormone  Functional sensitivity  Coefficient of variation
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