| 重组人血管内皮抑素联合TACE抗大鼠Walker-256细胞移植性肝癌血管生成的作用 |
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| 引用本文： | 张宝南,魏治鹏.重组人血管内皮抑素联合TACE抗大鼠Walker-256细胞移植性肝癌血管生成的作用[J].重庆医学,2011,40(32):3230-3231,3235,3220. |
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| 作者姓名： | 张宝南 魏治鹏 |
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| 作者单位： | 江苏省无锡市中医医院肿瘤科,214001 |
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| 基金项目： | 无锡市科学技术局基金资助项目(CSZ00858) |
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| 摘 要： | 目的 探讨重组人血管内皮抑素(rh-ES)联合肝动脉化疗栓塞术(TACE)对大鼠移植性Walker-256肝癌模型血管内皮生长因子(VEGF)表达和微血管密度(MVD)影响,评价rh-ES与TACE联合治疗对抑制大鼠移植性肝癌模型血管生成的疗效.方法 建立Wistar大鼠Walker-256肝癌模型,1周后随机分成治疗...
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| 关 键 词： | 癌 肝细胞 血管内皮生长因子类 重组人血管内皮抑素 肝动脉化疗栓塞术 微血管密度 |
Anti-angiogenesis effect of transcatheter arterial chemoembolization combining rh-ES in the rat Walker-256 hepatic implantation tumor |
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| Zhang Baonan,Wei Zhipeng.Anti-angiogenesis effect of transcatheter arterial chemoembolization combining rh-ES in the rat Walker-256 hepatic implantation tumor[J].Chongqing Medical Journal,2011,40(32):3230-3231,3235,3220. |
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| Authors: | Zhang Baonan Wei Zhipeng |
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| Institution: | Zhang Baonan,Wei Zhipeng(Department of Oncoma,Wuxi Hospital of Traditional Chinese Medicine,Wuxi,Jiangsu 214001,China) |
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| Abstract: | Objective To study the expression of microvascular density(MVD) and vascular endothelial growth factor(VEGF) in hepatic implantation tumor after transcatheter arterial chemoembolization(TACE) combining recombinant human endostatin(rh-ES)and to evaluate the therapeutic effect and angiogenesis of the rat hepatic implantation tumor.Methods According to the method introduced by the documents,forty rats with implanted tumors were randomly divided into two groups,with twenty in each group.The treatment group were... |
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| Keywords: | carcinoma hepatocellular vascular endothelial growth factor recombinant human endostatin transcatheter arterial chemoembolization microvessel density |
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