| 恙虫病患者检测三种细胞因子的临床意义 |
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| 引用本文： | 曹方余,季志宇,范丽芳,梁丽,张昌红.恙虫病患者检测三种细胞因子的临床意义[J].东南国防医药,2011,13(5):428-429. |
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| 作者姓名： | 曹方余 季志宇 范丽芳 梁丽 张昌红 |
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| 作者单位： | 解放军92医院感染管理科,福建南平,353000 |
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| 摘 要： | 目的 探讨恙虫病患者检测血清白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、粒细胞集落刺激因子( G-CSF)的临床意义.方法 采用ELISA方法检测恙虫病51例(观察组)治疗前后血清IL-6、TNF-α、G-CSF的浓度,并与健康体检者(对照组)比较分析.结果 与对照组比较,观察组治疗前IL-6、TNF-...
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| 关 键 词： | 恙虫病 白细胞介素-6 肿瘤坏死因子-α 粒细胞集落刺激因子 |
The clinical value of determination three cytokine levels in scrub typhus patients |
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| CAO Fang-yu,JI Zhi-yu,FAN Li-fang,LIANG Li,ZHANG Chang-hong.The clinical value of determination three cytokine levels in scrub typhus patients[J].Journal of Southeast China National Defence Medical Science,2011,13(5):428-429. |
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| Authors: | CAO Fang-yu JI Zhi-yu FAN Li-fang LIANG Li ZHANG Chang-hong |
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| Institution: | CAO Fang-yu,JI Zhi-yu,FAN Li-fang,LIANG Li,ZHANG Chang-hong.Department of Infection Management,92 Hospital of PLA,Nanpin,Fujian 353000,China |
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| Abstract: | Objective To explore the clinical value of determination IL-6,TNF-α and G-CSF level in scrub typhus patients.Methods The concentrations of IL-6,TNF-α and G-CSF were measured by using an enzyme-linked immunoassay in 51 patients with scrub typhus（experimental group）and in 51 health cases（control group）.IL-6,TNF-α and G-CSF were compared between control and experimental groups.2 weeks after therapy in experimental group,the three cytokine were detected again.Results The levels of IL-6,TNF-α and G-CSF in the scrub typhus group increased obviously compared to the control group（P〈0.05）,and these cytokine levels were significant lower 2 weeks after therapy in experimental group（P〈0.05）.Conclusion The determination of IL-6,TNF-α and G-CSF in scrub typhus patients has important clinical value. |
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| Keywords: | scrub typhus IL-6 TNF-α G-CSF |
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