| Toll样受体与癌症研究进展 |
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| 引用本文： | 王筱静,梁桂玲,王郡甫,许晓群. Toll样受体与癌症研究进展[J]. 国际肿瘤学杂志, 2013, 40(3): 166-169 |
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| 作者姓名： | 王筱静 梁桂玲 王郡甫 许晓群 |
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| 作者单位： | 王筱静 (250062 济南,山东省医学科学院基础医学研究所济南大学山东省医学科学院医学与生命科学学院;山东大学齐鲁医院)； 梁桂玲(山东大学齐鲁医院)；王郡甫(山东省医学科学院基础医学研究所济南大学山东省医学科学院医学与生命科学学院, 济南,250062)；许晓群(山东省医学科学院基础医学研究所济南大学山东省医学科学院医学与生命科学学院, 济南,250062)； |
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| 摘 要： | ![]()
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Toll-like receptors and cancer |
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| Affiliation: | Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan University School of Medical and Life Sciences, Jinan 250062, China |
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| Abstract: | ![]()
Toll-like receptor (TLR) is an important pattern recognition receptor (PRR) which participates in innate immunity and regulates adaptive immunity. TLR can be expressed in immune cells and malignant tumors recognize conservative molecular structure, mediate response of inflammation, tissue injury and repair, which plays an important role in the process of tumor. Research results about some molecules and signal pathways of TLR demonstrate that it can act anti or pro-tumor dual functions, which has an extensive prospects in prevention and treatment of tumor. |
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| Keywords: | Inflammation Neoplasms Epithelium Toll-like receptor |
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