补阳还五汤加伸筋草治疗脑梗死后痉挛型偏瘫疗效研究

目的:探讨补阳还五汤重用伸筋草治疗脑梗死后痉挛型偏瘫的作用。方法:收集脑梗死后痉挛型偏瘫患者共88例,分为两组,对照组44例,西医治疗加康复训练和补阳还五汤治疗; 研究组44例,西医治疗加康复训练及补阳还五汤重用伸筋草治疗。比较治疗前后患者患侧上下肢肌张力、临床疗效、NIHSS、日常生活能力Barthel指数以及上下肢运动功能和不良反应发生率。结果:治疗后,两组患者患侧上下肢肌张力≤1级者占比均升高,且研究组中≤1级者占比均高于对照组,组间比较有统计学意义(P<0.05)。两组临床疗效等级分布和总有效率比较,差异有统计学意义(P<0.05)。治疗后两组患者NIHSS评分均降低,且研究组NIHSS评分低于对照组,治疗后两组患者Barthel指数和患侧上下肢FMA评分均升高,且研究组均高于对照组,组间比较有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:补阳还五汤重用伸筋草能够显著降低患者患侧上下肢肌张力,改善临床疗效和神经功能缺损,提高患者日常生活能力和患侧运动功能,且安全性良好。

Efficacy study on Buyang Huanwu decoction with lycopodium clavatum on spastic hemiplegia after cerebral infarction

Objective:To investigate the effect of Buyang Huanwu decoction with reuse of lycopodium clavatum on spastic hemiplegia after cerebral infarction.Methods:88 patients with spastic hemiplegia after cerebral infarction were selected as the control group 44 cases,western medicine treatment,rehabilitation training and Buyang Huanwu decoction; the study group 44 cases western medicine treatment,rehabilitation training and Buyang Huanwu decoction with reuse of lycopodium clavatum.The changes of upper limb muscle tension and lower extremity muscle tension,the clinical efficacy,NIHSS,the ability of daily living Barthel index,the motor function of upper and lower extremities and incidence of adverse reactions were compared.Results:After treatment,the proportions of patients with ≤ grade 1 of muscle tension in the upper and lower extremities of the two groups were higher than before treatment,which in the study group were higher than those in the control group,with statistically significant differences(P<0.05).There were significant differences in clinical efficacy grade distribution and total effective rates between the two groups(P<0.05).The NIHSS scores of the two groups decreased after treatment,of which the study group was lower than that in the control group.The Barthel indexes and FMA scores of the upper and lower extremities of the two groups increased after treatment,of which the study group were higher than those in the control group.The differences were statistically significant(P<0.05).The incidence of adverse reactions between the two groups was no satistically significant(P>0.05).Conclusion:Buyang Huanwu decoction with reuse of lycopodium clavatum can significantly reduce the muscle tension of the upper and lower limbs and improve the clinical efficacy and neurological deficit,improve the daily living ability of the patients and the motor function of the affected side and the safety.