定量磁共振成像技术原理及研究进展

定量磁共振成像技术近年来已广泛用于各个疾病的研究之中，最佳定量磁共振成像技术的应用将会对疾病的早期诊断和治疗产生更好的帮助。本文从成像原理出发对目前常见定量技术进行分类，介绍了化学交换饱和转移技术、化学位移同反相位技术、磁共振波谱、定量磁敏感图、弛豫率成像等技术的原理以及研究进展，最后对各个技术进行汇总分析。结果表明磁共振定量技术种类繁多，定量物质种类广泛。且部分定量磁共振成像技术之间存在交叉，一种技术可定量多种物质，多种技术可用于一种与疾病相关的物质定量研究。尽管目前有相关研究对定量同一物质的多种技术进行比较，但比较结果仍需进一步探索。本文的分析结果便于了解常见定量磁共振成像技术及其研究进展，可为临床诊疗研究提供可借鉴的依据。 

Principle and research progress of quantitative magnetic resonance imaging

Quantitative magnetic resonance imaging has been widely used in the study of various diseases in recent years. The best application of quantitative magnetic resonance imaging will be helpful for early diagnosis and treatment. In this paper, several common quantitative MRI imaging techniques are classified according to the imaging principle. The principles and research progress of chemical exchange saturation transfer, chemical shift imaging, magnetic resonance spectrum, quantitative susceptibility mapping, and relaxation rate mapping technique are introduced. Finally, this paper analyzed the research progress. The analysis results show that there are many kinds of quantitative magnetic resonance imaging techniques and quantitative substances. Moreover, some quantitative magnetic resonance imaging techniques are overlapping. One technology can quantify multiple substances, and many technologies can be used for quantitative research of a disease-related substance. Although relevant studies have been carried out to compare various techniques for quantifying the same substance, the comparison results still need to be further explored. This paper's analysis results are convenient to understand the standard quantitative magnetic resonance imaging technology and its research progress and provide a reference basis for clinical diagnosis and treatment research.