Primary mucosa-associated lymphoid tissue lymphoma in the midbrain: A case report |
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Authors: | Yong-Rui Zhao Rong-Hua Hu Rui Wu Jian-Kun Xu |
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Institution: | Yong-Rui Zhao, Jian-Kun Xu, Department of Radiation Oncology, Xuanwu Hospital, Capital Medical University, Beijing 100053, ChinaRong-Hua Hu, Department of Hematology, Xuanwu Hospital, Capital Medical University, Beijing 100053, ChinaRui Wu, Department of Pathology, Peking University Third Hospital, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China |
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Abstract: | BACKGROUNDPrimary non-dural central nervous system mucosa-associated lymphoid tissue (MALT) lymphoma is a rare indolent B-cell lymphoma, with only a few reported cases worldwide.CASE SUMMARYA 33-year-old man presented with a 5-mo history of left blepharoptosis and a 4-mo history of right limb numbness and weakness. Magnetic resonance imaging showed a significantly enhanced mass in the left midbrain. Subsequent positron emission tomography revealed that the lesion had increased glucose uptake. A stereotactic robotic biopsy supported a diagnosis of MALT lymphoma. Then he was treated with radiation therapy (30Gy/15F), which resulted in complete remission. We also review the literature on brain parenchymal-based MALT lymphoma, including the clinical presentation, treatment options, and outcomes.CONCLUSIONAlthough there is no consensus on the optimal treatment for this rare disease, patients can respond well when treated with radiotherapy alone. |
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Keywords: | Mucosa-associated lymphoid tissue lymphoma B-cell lymphoma Central nervous system Brain parenchyma Radiotherapy Case report |
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