白内障围手术期结膜囊菌群分布及药敏试验

目的 分析白内障围手术期结膜囊菌群的分布及药敏试验结果。方法 选取264例白内障患者,分别在患者入院后、手术消毒前、手术消毒后、手术结束后四个时间点取样,进行细菌培养及药敏试验,比较不同时期的细菌培养结果和药敏结果。结果 入院后结膜囊细菌培养阳性率明显高于手术消毒前、手术消毒后及手术结束后;入院后结膜囊细菌培养以表皮葡萄球菌为主;革兰氏阳性球菌对头孢西丁、加替沙星、左氧氟沙星等敏感性较高。结论 表皮葡萄球菌是结膜囊最常见的细菌,术前应常规应用抗生素点眼,聚维酮碘冲洗结膜囊等来预防术后感染性眼内炎。

Investigation of conjunctival sac bacteria and drug susceptibility in perioperative of cataract

Objective To study conjunctival sac bacteria and drug susceptibility in perioperative of cataract.Methods Totally 264 cataract patients were selected and sampled at four time points after admission,before surgical disinfection,after surgical disinfection,and after surgery.Bacterial culture and drug sensitivity tests were conducted to compare the bacterial culture and drug sensitivity results in different periods.Results The positive rate of bacterial culture of conjunctival sac after admission was significantly higher than that before surgical disinfection,after surgical disinfection,and after surgery.After admission,the bacterial culture of conjunctival sac was mainly staphylococcus epidermidis.Gram-positive cocci are more sensitive to cefoxitin,gatifloxacin and levofloxacin.Conclusion Staphylococcus epidermidis is the most common bacteria in conjunctival sac.Antibiotics should be routinely applied before the operation,and providone iodine should be used to wash conjunctival sac to prevent posto-perative infectious endophthalmitis.