首页 | 本学科首页   官方微博 | 高级检索  
     

表达狂犬病毒糖蛋白的重组痘苗病毒对狗的免疫效果观察
引用本文:蔡兵 应保龄. 表达狂犬病毒糖蛋白的重组痘苗病毒对狗的免疫效果观察[J]. 中国人兽共患病杂志, 1993, 9(3): 2-3
作者姓名:蔡兵 应保龄
作者单位:卫生部武汉生物制品研究所(蔡兵,应保龄,胡巧玲,陈乃民,李承平,兰华庚,江立新),卫生部武汉生物制品研究所(朱家鸿)
摘    要:
用表达狂犬病毒糖蛋白的两株重组痘苗病毒对狗口服、划痕和肌肉注射三种途径的免疫效果进行观察。结果口服免疫未见抗体阳转,而划痕和肌注免疫在第七天就能诱导中和抗体。中和抗体滴度达642。以肌肉注射、皮下注射和脚掌注射免疫小鼠,亦获得较好的免疫效果。

关 键 词:  重组痘苗病毒  狂犬病毒糖蛋白

Observation on Immunoeffects of Recombinant Vaccinia Virus Expressing Rabies Virus Glycoprotein Gene to Dogs
Cai Bing,et al. Observation on Immunoeffects of Recombinant Vaccinia Virus Expressing Rabies Virus Glycoprotein Gene to Dogs[J]. Chinese Journal of Zoonoses, 1993, 9(3): 2-3
Authors:Cai Bing  et al
Abstract:
Two strains of recombinant vaccinia virus expressing rabies glycoprotein gene were inoculated into dogs by three ways. High tilers of neutralizing antibodies were induced by scarification and intramuscular routes, but there was no seroconversion when being immunized by oral route Immunologic effects were also observed when the recombinants were inoculated into mice by various ways.
Keywords:Dog    Recombinant vaccinia virus    Rabies glycoprotein.  
本文献已被 CNKI 维普 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号