足月低出生体重儿危险因素的Meta分析

目的 综合评价足月低出生体重儿的危险因素。方法 检索中文数据库（中国生物医学文献数据库、中国期刊全文数据库、数字化期刊全文数据库）、英文数据库（Medline、Embase）中1980年至2016年2月25日期间公开发表的相关文献，并按照事先确定的纳入与排除标准剔除不符合要求的文献，对纳入文献采用Stata 13.0软件进行Meta分析。结果 共纳入23篇文献，包含278 020例研究对象。胎儿性别为女（合并OR=1.60，95% CI：1.49～1.72）、产前检查次数较少（合并OR=1.81，95% CI：1.54～2.11）、母亲被动吸烟（合并OR=1.49，95% CI：1.08～2.06）、妊娠期高血压（合并OR=2.96，95% CI：1.85～4.74）、羊水过少（合并OR=2.71，95% CI：1.87～3.93）是足月低出生体重儿的危险因素。结论 针对足月低出生体重儿的危险因素，应鼓励孕妇产前检查，及时发现并诊治孕妇妊娠期合并症，并通过相关宣教促使孕妇主动避免被动吸烟，从而提升新生儿出生质量。

Meta-analysis on partial risk factors of full-term infants with low birth weight

Objective To evaluate the risk factors of full-term infants with low birth weight. Methods All related Chinese and English literatures published from 1980 to February 25, 2016 were collected from CBM, CNKI, Wang Fang Data, Medline and Embase databases, and screened with inclusion and exclusion criteria and Stata13.0 software was used in this Meta-analysis. Results Twenty three studies were included and there were 278 020 subjects. Female infants (pooled OR=1.60, 95%CI:1.49-1.72), less antenatal care visits (pooled OR=1.81, 95%CI:1.54-2.11), maternal passive smoking (pooled OR=1.49, 95%CI:1.08-2.06), pregnancy-induced hypertension (pooled OR=2.96, 95%CI:1.85-4.74) and hypamnion (pooled OR=2.71, 95%CI:1.87-3.93) were the risk factors for full-term infants with low birth weight. Conclusion Departments of maternal and health care should encourage pregnant women to have antenatal care visits to find and treat their pregnancy complications, and avoid passive smoking actively through health education for the purpose to prompt the birth quality of infants.