| 用SPSS拟合药物溶出度Weibull参数 |
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| 引用本文： | 黄献,刘裕恒,莫志江. 用SPSS拟合药物溶出度Weibull参数[J]. 中国药房, 2006, 17(14): 1079-1081 |
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| 作者姓名： | 黄献 刘裕恒 莫志江 |
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| 作者单位： | 1. 广西壮族自治区人民医院药剂科,南宁市,530021
2. 广西壮族自治区人民医院介入科,南宁市,530021 |
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| 摘 要： | 目的介绍用SPSS拟合药物溶出度Weibull参数。方法采用SPSS软件经非线性回归拟合Weibull模型(Y=1—e-(t-τ)m/t0)处理药物溶出度数参数。结果SPSS与目前其它方法拟合的Weibull模型处理药物溶出度参数比较,其准确性高,计算过程简便、快速。结论本方法拟合药物Weibull参数操作简单,计算结果准确。
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| 关 键 词： | 药物溶出度 Weibull分布 SPSS 非线性回归 |
| 文章编号： | 1001-0408(2006)14-1079-03 |
| 收稿时间： | 2005-12-08 |
| 修稿时间： | 2006-02-28 |
The Resolution with SPSS Analyzing for Weibull''''s Distribution of Drug Dissolution Rate |
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| HUANG Xian,LIU Yuheng,MO Zhijiang. The Resolution with SPSS Analyzing for Weibull''''s Distribution of Drug Dissolution Rate[J]. China Pharmacy, 2006, 17(14): 1079-1081 |
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| Authors: | HUANG Xian LIU Yuheng MO Zhijiang |
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| Abstract: | OBJECTIVE: To calculate the parameters of the Weibull's distribution of the drug by SPSS.METHOD: The detail method of resolution with SPSS analyzing for the treatment of the parameters on drug dissolution rate in use of Weibull's model(Y=1—e-(t-τ)m/t 0)were presented. RESULTS: The method for the determination of the parameters in Weibull's distribution on drug dissolution rate through SPSS nonlinear regression was simple, rapid and accurate while compared with other methods. CONCLUSION: The method is simple and practical. It can be used to calculate the parameters of the Weibull's distribution of the drug. |
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| Keywords: | SPSS |
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