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胰岛素样生长因子-I与代谢综合征及胰岛素抵抗的关系
引用本文:应小盈,王长谦,何奔. 胰岛素样生长因子-I与代谢综合征及胰岛素抵抗的关系[J]. 心脏杂志, 2006, 18(5): 496-498,502. DOI: 10.13191/j.chj.2006.05.20.yingxy.005
作者姓名:应小盈  王长谦  何奔
作者单位:上海第二医科大学附属仁济医院心内科,上海,200001
摘    要:目的为了研究血清胰岛素样生长因子-I(IGF-I)与代谢综合征、胰岛素抵抗和高胰岛素血症之间的关系。方法本研究分析了75名住院患者冠脉造影结果、代谢综合征的相关情况和血清IGF-I的浓度。结果代谢综合征患者的血清IGF-I水平明显低于非代谢综合征患者,且血清IGF-I水平与血清胆固醇,体质量指数呈负相关,并且在非糖尿病患者中,IGF-I值与HOMA胰岛素抵抗指数有相关性。结论血清IGF-I水平与胰岛素抵抗有关,与反映胰岛素抵抗的指标如体内脂肪含量和脂代谢紊乱具有相关性。

关 键 词:代谢综合征   胰岛素抵抗   胰岛素样生长因子-I   体质量指数
文章编号:1009-7236(2006)05-496-03
收稿时间:2005-09-02
修稿时间:2005-09-022005-12-06

Relationship between insulin-like growth factor I and metabolic syndrome
YING Xiao-ying,WANG Chang-qian,HE Ben. Relationship between insulin-like growth factor I and metabolic syndrome[J]. Chinese Heart Journal, 2006, 18(5): 496-498,502. DOI: 10.13191/j.chj.2006.05.20.yingxy.005
Authors:YING Xiao-ying  WANG Chang-qian  HE Ben
Affiliation:Department of Cardiology, Renji Hospital Affiliated to Shanghai Second Medical University, Shanghai 200001, China
Abstract:AIM To explore the relationship between serum insulin-like growth factor I(IGF-I) and metabolic syndrome(MS),insulin resistance and hyperinsulinemia.METHODS The coronary artery angiography,MS and serum IGF-I level of 75 in-patients.RESULTS We found that the serum IGF-I level was much lower in the patients with MS than that in non-MS patients.There was a negative relationship between serum IGF-1 and total cholesterol(TC) and body mass index(BMI),in addition it was somewhat related with HOMA insulin resistance index in non-diabetes patients.CONCLUSION serum IGF-I is associated with insulin resistance,some dislipidemia and BMI.
Keywords:imetabolic syndrome  nsulin resistance  insulin-like growth factor I  body mass index
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