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血清髓过氧化物酶与急性冠状动脉综合征的相关性
引用本文:朴星杰,崔兰,宋京郁,李太升. 血清髓过氧化物酶与急性冠状动脉综合征的相关性[J]. 延边医学院学报, 2010, 33(2): 128-130
作者姓名:朴星杰  崔兰  宋京郁  李太升
作者单位:朴星杰,崔兰(延边大学附属医院,心内科,吉林,延吉,133000);宋京郁,李太升(延边大学基础医学院,病理学与法医学教研部,吉林,延吉,133000) 
基金项目:延边大学研科合字第99号 
摘    要:
[目的]探讨血清髓过氧化物酶(MPO)与急性冠状动脉综合征(ACS)的相关关系.[方法]选择用Judkin’s法行选择性冠状动脉造影检查的84例入选者分为不稳定型心绞痛(UAP)组27例、急性心肌梗死(AMI)组28例和正常对照组29例,采用ELISA法测定血清MPO水平.[结果]UAP组和AMI组患者血清MPO水平均显著高于正常对照组,AMI组MPO水平显著高于UAP组;再依据病变范围及狭窄程度对UAP组和AMI组进行分组观察,见随着病变范围的增加和狭窄程度的提高,MPO水平均呈现出显著增高趋势.[结论]ACS患者血清MPO水平显著升高,而血清MPO水平与病变范围及狭窄程度呈正相关.

关 键 词:过氧化物酶  心绞痛,不稳定型  心肌梗死

Relative study on levels of serum myeloperoxidase and acute coronary syndrome
PIAO Xing-jie,CUI Lan,SONG Jing-yu,LI Tai-sheng. Relative study on levels of serum myeloperoxidase and acute coronary syndrome[J]. Journal of Medical Science Yanbian University, 2010, 33(2): 128-130
Authors:PIAO Xing-jie  CUI Lan  SONG Jing-yu  LI Tai-sheng
Affiliation:1.Department of Cardiology,Affiliated Hospital of Yanbian University;2.Department of Pathology and Forensic Medicine,Yanbian University College of Basic Medicine:Yanji 133000,Jilin,China)
Abstract:
OBJECTIVE To study the relationship between levels of serum myeloperoxidase(MPO)and acute coronary syndrome(ACS).METHODS Using Judkin's method,84 patients performed with the selective coronary angiography were divided into UAP group(n=27),AMI group(n=28)and control group(n=29).The levels of serum MPO were detected by ELISA.RESULTS The levels of serum MPO were significantly higher in UAP group and AMI group than in control group and in AMI group than in UAP group,and had significantly increasing tendency along with the extension of lesion and aggravation of stenotic degree.CONCLUSION The levels of serum MPO are significantly increased in ACS patients and positive correlation with the extension of lesion and stenotic degree.
Keywords:peroxidase  angina  unstable  myocardial infarction
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