Interaction of concanavalin A with enveloped viruses and host cells

HVJ (Sendai virus) and herpes simplex virus, which are both enveloped viruses, have receptors for concanavalin A, but poliovirus, which has no envelope, has no receptors. The HA activity of HVJ was not lost on exposure to concanavalin A; it seems that the sites on HVJ adsorbing concanavalin A differ from the active site of its hemagglutinin.