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Loss of 9p leads to p16INK4A down-regulation and enables RB/E2F1-dependent cell cycle promotion in gastrointestinal stromal tumours (GISTs)
Authors:Haller F  Löbke C  Ruschhaupt M  Cameron S  Schulten H-J  Schwager S  von Heydebreck A  Gunawan B  Langer C  Ramadori G  Sültmann H  Poustka A  Korf U  Füzesi L
Institution:1. Department of Pathology, Georg August University, G?ttingen, Germany;2. These authors contributed equally to this work;3. Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, Germany;4. Department of Medical Informatics, Biometrics, and Epidemiology, Medical School, Ludwig Maximilians University, Munich, Germany;5. Department of Gastroenterology and Endocrinology, Georg August University, G?ttingen, Germany;6. Department of Bio‐ and Chemoinformatics, Merck KGaA, Darmstadt, Germany;7. Department of General and Visceral Surgery, Georg August University, G?ttingen, Germany
Abstract:
Keywords:GIST  p16INK4A  RB  E2F1  mRNA  proteomics  cancer  cell cycle  RPPA
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