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原发性骨质疏松症的诊断和防治
引用本文:孟迅吾. 原发性骨质疏松症的诊断和防治[J]. 中华内分泌代谢杂志, 2006, 22(3): 205-208
作者姓名:孟迅吾
作者单位:100730,中国医学科学院,北京协和医院内分泌科
摘    要:
骨质疏松症是以骨强度降低、骨折危险性增加为主要表现的骨骼疾病,骨强度反映了骨密度和骨质量的完整性。本文简要介绍现今对原发性骨质疏松症的诊断和防治。诊断基于双能X线吸收法测定的、由世界卫生组织制定标准的骨密度值。预防应置于首位,重视对医师和群众的宣教,针对认识上存在的误区。干预的阈值还存在不同的意见,尚须进一步探讨。药物治疗已有不少进展,选择用药应根据本病的特点、循证医学的证据、降低骨折发生和成本及效益分析而进行全面衡量,作出决策。

关 键 词:骨质疏松 骨密度 危险因素 干预阈值 诊断 治疗
收稿时间:2006-05-04
修稿时间:2006-05-04

Diagnosis, prevention and therapy of primary osteoporosis
MENG Xun-wu. Diagnosis, prevention and therapy of primary osteoporosis[J]. Chinese Journal of Endocrinology and Metabolism, 2006, 22(3): 205-208
Authors:MENG Xun-wu
Affiliation:Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing 100730
Abstract:
Osteoporosis is a skeletal disorder characterized by compromised bone strength predisposing a person to an increased risk of fracture.Bone strength primarily reflects the integration of bone density and bone quality.Here the current status of diagnosis,prevention and treatment on osteoporosis is introduced briefly.The diagnosis based on the criteria of World Health Orgnization by bone mineral density measurement(Dual-energy X- ray absorptiometry).Prevention is of the primary importance,pay more attention to the education to people and medical doctors for correcting their misleading concept.There are different opinions about intervention threshold which has to be investigated further.More progress has been made on osteoporosis therapy,according to the feature of illness,evidence-based medicine,analysis on reducing fracture risk and cost-effectiveness help to determine the drug selection.
Keywords:Osteoporosis   Bone density   Risk factors   Intervention threshold   Diagnosis   Therapy
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