CSC应用3D-OCT的临床分析

目的:应用三维光学相干断层扫描(3D-OCT)探讨中心性浆液性脉络膜视网膜病变(CSC)的形态学特征与视力的相关性。方法:对46例50眼CSC患者进行了3D-OCT检查,测量出CSC患者黄斑区神经上皮层脱离的高度、范围及容积,并利用SPSS13.0统计学软件对所得结果与视力进行相关分析。结果:黄斑区神经上皮层脱离高度与视力呈负相关关系(r=-0.78,P=0.00),而与神经上皮脱离范围、容积之间无负相关关系(r=-0.39,P=0.26;r=-0.09,P=0.80)。结论:CSC黄斑区神经上皮层脱离的高度为影响视力的主要因素,高分辨率的3D-OCT能在CSC患眼上获得类似于眼组织病理学改变的影像,从而对CSC的诊断、鉴别诊断、病变程度分析及治疗后的病情监测具有临床应用价值。

Clinical analysis of central serous chorio-retinopathy under 3D-optical cohe-rence tomography

AIM:To discuss morphological character of central serous chorioretinopathy(CSC) under 3D-optical coherence tomography(OCT) and correlation with visual acuity.METHODS:Totally 46 patients(50 eyes)were checked with 3D-OCT,heights,ranges and volumes of nerve epithelial layer detachment in macular areas were measured,and correlation analysis of statistical software SPSS 13.0 was used to calculate correlation between the results above and visual acuity.RESULTS:There was a negative correlation between height of detachment in macular areas and visual acuity(r=-0.78,P=0.00),but no correlation between ranges,volumes and visual acuity(r=-0.39,P=0.26;r=-0.09,P=0.80).CONCLUSION:Heights of detachment in macular areas were the main factor that influenced visual acuity,high resolution 3D-OCT can get images approaching to histopathology of ophthalmology in CSC affected eyes,so as to get clinical implications in analyzing diagnosis,differential diagnosis,degrees of disease and was most valuable in supervision after the therapy.