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Rectal Administration of Lipopolysaccharide and Ovalbumin Ameliorates Acute Murine Colitis
Authors:Jong Pil Im  Byong Duk Ye  Jung Mogg Kim  Hyun Chae Jung  In Sung Song  Joo Sung Kim
Affiliation:(1) Department of Internal Medicine Liver Research Institute, Seoul National University College of Medicine, 28 Yongon-Dong, Chongno-Gu, Seoul, 110-744, Korea;(2) Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Ulsan, Korea;(3) Department of Microbiology, Hanyang University College of Medicine, Seoul, Korea;
Abstract:

Background  

Repeated challenges of lipopolysaccharide (LPS) could reduce the expression of proinflammatory cytokines in vitro, and oral administration of ovalbumin (OVA) induces mucosal tolerance in vivo. However, the effect of local administration of LPS and OVA on experimental colitis in vivo remains unknown.
Keywords:
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