萎软紫菀化学成分的研究

目的 对萎软紫菀Aster flaccidus全草的化学成分进行分离研究.方法 采用正、反相硅胶柱进行分离纯化,用物理化学和光谱学方法鉴定化合物的结构.结果 从紫菀属植物萎软紫菀全草中分离鉴定出14个化合物,分别为2-oxo-isocostic acid(1)、单萜环烯醚苷(2)、山柰酚-3-O-β-D-葡萄糖苷(3)、1β,6α-二羟基桉烷-4(15)-烯(4)、6β-丙酸基-1,10-脱氢呋喃艾里莫芬型烷(5)、印乌头碱(6)、羽扇豆醇(7)、甘草素(8)、黄芹素(9)、苜蓿素(10)、松柏醛(11)、木栓酮(12)、芹菜素(13)、对羟基苯甲酸(14).结论 其中化合物2～7为该属植物中首次分离得到,化合物1～10、13为该植物中首次分离得到.

Chemical constituents of Aster flaccidus

Objective To study the chemical constituents of Aster flaccidus.Methods Compounds were separated by positive and negative silica gel column chromatography,and their structures were identified by spectral data and physicochemical characteristic.Results Nine compounds were obtained and identified as 2-oxo-isocostic acid(1),mussaenoside(2),kaempferol-3-O-β-Dglucopyranoside(3),1β,6α-dihydroxyeudesm-4(15)-ene(4),6β-propionyloxy-1,10-dehydrofuranoeremophil-9-on(5),indaconitine(6),lupeol(7),liquiritigenin(8),apigenin(9),tricine(10),coniferyl aldehyde(11),friedelin(12),apigenin(13),and p-hydroxybenzoicacid(14).Conclusion Compounds 2—7 are found from plants in Aster L.for the first time,and compounds 1—10 and 13 are obtained from A.flaccidus for the first time.