半夏褐变抑制条件及其对药理作用的影响

目的 研究抑制半夏干燥过程中引起褐变的条件,并考察其对半夏镇咳、祛痰作用的影响.方法 使用色彩色差计测量各种方法处理的半夏干燥过程中表面颜色的变化值,优选最佳处理条件,并辅以镇咳及祛痰实验验证其对半夏药理作用的影响.结果 不同pH值的酸性溶液抑制半夏的酶促褐变反应没有显著的差异,酸性越强,颜色变化越小;采用醋酸处理不会影响半夏的镇咳、祛痰作用.结论 酸性环境能够抑制半夏的褐变反应,且不会对半夏的药理作用产生显著影响.

Inhibition of Pinelliae Rhizoma browning and its effects on pharmacological actions

Objective To study the inhibition conditions of browning in the drying process of Pinellia Rhizoma(PR) and observe its impact on the antitussiue and expectorant effects.Methods The surface color data of drying PR were measured by colcorimeter to optimize the best conditions,supplemented by experimental verification of its effects on pharmacological actions.Results There were no significant difference among inhibition of different pH values on PR browning.The stronger the acidity was the smaller the color changed.The use of acetic acid did not affect the antitussiue and expectorant effects of RP.Conclusion Acidic environment could inhibit browning reactions,but will not change the pharmacological effects of PR significantly.