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| 胎儿颈项透明层厚度在诊断染色体异常中的应用价值 | |
| 引用本文： | 陈文艳,郑爱娟,胡梅青. 胎儿颈项透明层厚度在诊断染色体异常中的应用价值[J]. 中国妇幼保健, 2013, 28(9): 1491-1493 |
| 作者姓名： | 陈文艳 郑爱娟 胡梅青 |
| 作者单位： | 浙江省舟山市妇幼保健院 316000 |
| 基金项目： | 浙江省卫生厅科研课题(项目编号：2009B159) |
| 摘 要： | 目的:探讨胎儿颈项透明层(NT)增厚与胎儿染色体异常的关系。方法:2009年2月～2012年1月在舟山市妇幼保健院进行产前检查的312名NT增厚孕妇行胎儿染色体核型分析。结果:312名孕妇NT增厚孕妇中14例胎儿为染色体核型异常,比例为4.49%,并且NT≥3.0 mm对染色体异常的诊断灵敏度为96.45%,特异性为94.45%。结论:NT增厚对染色体异常的早期筛查具有重要意义,NT≥3.0 mm是进行染色体筛查的一个重要的指标。 |
| 关 键 词： | 颈项透明层厚度 染色体异常 产前筛查 |
Application value of fetal nuchal translucency thickness in diagnosis of chromosomal abnormality |
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| Abstract: | Objective:To explore the relationship between nuchal translucency thickness(NT) thickening and fetal chromosomal abnormality.Methods:From February 2009 to January 2012,312 pregnant women with NT thickening who received prenatal examination in the hospital received fetal karyotype analysis.Results:Among 312 pregnant women with NT thickening,14 fetuses were found with chromosomal abnormality,the proportion was 4.49%,and the sensitivity and specificity of NT≥3.0 mm for diagnosis of chromosomal abnormality was 96.45% and 94.45%,respectively.Conclusion:NT thickening has important significance for early screening of chromosomal abnormality,NT≥3.0 mm is an important index for chromosomal screening. |
| Keywords: | Nuchal translucency thickness Chromosomal abnormality Prenatal screening |
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