不良妊娠结局影响因素的病例对照研究

目的:探讨不良妊娠结局发生的影响因素,为不良妊娠结局综合防治提供参考依据。方法:采用1∶2匹配病例对照研究方法,分析不良妊娠结局发生的影响因素。结果:单因素条件Logistic回归分析结果显示:不良妊娠结局组与无不良妊娠结局组的孕妇文化程度、全家人均月收入、孕前健康教育、月经是否规则、此次妊娠患有妊娠期高血压疾病等差异有统计学意义(P<0.05);多因素条件Logistic回归分析结果表明:孕妇文化程度、此次妊娠患有妊娠期高血压疾病、参加体育活动、妊娠次数被引入回归方程。结论:孕妇文化程度高、参加体育活动、妊娠次数少为不良妊娠结局发生的保护因素,而患有妊娠期高血压疾病为不良妊娠结局发生的危险因素。

A case-control study on influence factors of adverse pregnancy outcome

Objective:To explore the influence factors of adverse pregnancy outcome,and provide the scientific evidence for comprehensive prevention of adverse pregnancy outcome.Methods:A 1∶ 2 matched case-control study was conducted to explore the influence factors of adverse pregnancy outcome.Results:Univariate conditional logistic regression analysis showed that the significant factors included maternal education level,family per capita monthly income,pre-pregnancy health education,menstrual history,hypertensive disorder complicating pregnancy between adverse pregnancy outcome group and no adverse pregnancy outcome group.Multivariate conditional logistic regression analysis showed: maternal educational level(OR=0.541),hypertensive disorder complicating pregnancy(OR=10.966),sports activities(OR=0.322) and numbers of pregnancy(OR=0.565) went into regression equation.Conclusion:The protective factors of adverse pregnancy outcome include high education level,participating in sports activities,and reduction of numbers of pregnancy.Hypertensive disorder complicating pregnancy is the risk factor of adverse pregnancy outcome.